一、研究方向
天然免疫识别与调控;畜禽肠道共生菌
教授推荐:唐博(女),吉林大学教授、博导,兽医大咖
二、教授课程
本科:动物生理学,动物机能学实验技术
硕士:动物生理学前沿,动物机能学实验技术
三、教育简历
1989.9-1994.6 白求恩医科大学,医学学士
1999.9-2003.6 解放军军需大学,农学硕士
2012.9-2019.6 吉林大学,农学博士
四、工作简历
1994.7-2004.7 解放军军需大学训练部,馆员
2004.8-2005.12 中科院文献情报中心,馆员
2006.8-2009.5 加拿大戴尔豪斯大学微生物与免疫学系,访问学者
2010.1-2010.8 吉林大学动物医学学院,讲师
2010.9-2021.8 吉林大学动物医学学院,副教授
2021.9- 吉林大学动物医学学院,教授
五、论文
1、Yu Gao#, Jian-Gang Zhang#, Zhen-Zhen Liu, Ke Ma, Xiao-Qi Lin, Jia-Bao Zhang, Wei Chen, YongJun Yang. Extracellular trap can be trained as a memory response. Virulence. 2022, 13(1):471-482
2、Zhen-Zhen Liu#, Wei Chen#, Cheng-Kai Zhou, Ke Ma, Yu Gao, Yong-Jun Yang. Stimulator of Interferon Genes (STING) Promotes Staphylococcus aureus-Induced Extracellular Traps Formation via the ROS-ERK Signaling Pathway. Front Cell Dev Biol. 2022, 10:836880
3、Ke Ma#, Wei Chen#, Shi-Qing Yan, Zhen-Zhen Liu, Xiao-Qi Lin, Jia-Bao Zhang, Yu Gao, Tao Wang, Jian-Gang Zhang, Yong-Jun Yang. Purification, Characterization, Mode of Action, and Application of Jileicin, a Novel Antimicrobial from Paenibacillus jilinensis YPG26. J Agric Food Chem. 2022, 70(18):5570-5578
4、Ke Ma#, Wei Chen#, Shi‑Qing Yan, Xiao‑Qi Lin, Zhen‑Zhen Liu, Jia‑Bao Zhang, Yu Gao, Yong‑Jun Yang. Genome mining reveals polysaccharide-degrading potential and new antimicrobial gene clusters of novel intestinal bacterium Paenibacillus jilinensis sp. nov. BMC Genomics, 2022, 23:380
5、Zhen-Zhen Liu#, Yong-Jun Yang#, Feng-Hua Zhou, Ke Ma, Xiao-Qi Lin, Shi-Qing Yan, Yu Gao,Wei Chen. GSDMD contributes to host defence against Staphylococcus aureus skin infection by suppressing the Cxcl1–Cxcr2 axis. Veterinary Research, 2021 May 19;52(1):71
6、Zhen-Zhen Liu#, Yong-Jun Yang#, Cheng-Kai Zhou, Shi-Qing Yan, Ke Ma, Yu Gao and Wei Chen. STING Contributes to Host Defense Against Staphylococcus aureus Pneumonia Through Suppressing Necroptosis. Front. Immunol., 2021 May 31;12:636861
7、Hu GQ#, Yang YJ#, Qin XX, Qi S, Zhang J, Yu SX, Du CT, Chen W. Salmonella Outer Protein B Suppresses Colitis Development via Protecting Cell From Necroptosis. Front Cell Infect Microbiol. 2019 Apr 9;9:87
8、Chen W#, Yu SX#, Zhou FH, Zhang XJ, Gao WY, Li KY, Liu ZZ, Han WY, Yang YJ. DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice. Front Immunol. 2019 Mar 18;10:474
9、Zhang J#, Qin D#, Yang YJ#, Hu GQ, Qin XX, Du CT, Chen W. MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.Mol Immunol. 2019 Mar;107:132-141
10、Yu SX#, Chen W#, Liu ZZ, Zhou FH, Yan SQ, Hu GQ, Qin XX, Zhang J, Ma K, Du CT, Gu JM, Deng XM, Han WY, Yang YJ. Non-Hematopoietic MLKL Protects Against Salmonella Mucosal Infection by Enhancing Inflammasome Activation. Front Immunol. 2018 Feb 2;9:119
11、Yu SX#, Zhou FH#, Chen W#, Jiang GM, Du CT, Hu GQ, Liu ZZ, Yan SQ, Gu JM, Deng XM, Lin TJ, Duan EK, Yang YJ. Decidual Stromal Cell Necroptosis Contributes to Polyinosinic-Polycytidylic Acid-Triggered Abnormal Murine Pregnancy. Front Immunol. 2017 Aug 2;8:916
12、Yu SX#, Chen W#, Hu XZ, Feng SY, Li KY, Qi S, Lei QQ, Hu GQ, Li N, Zhou FH, Ma CY, Du CT, Yang YJ. Liver X receptors agonists suppress NLRP3 inflammasome activation. Cytokine. 2017 Mar;91:30-37
13、Lv H#, Zhu C#, Liao Y, Gao Y, Lu G, Zhong W, Zheng Y, Chen W, Ci X. Tenuigenin ameliorates acute lung injury by inhibiting NF-κB and MAPK signalling pathways. Respir Physiol Neurobiol. 2015 Sep 15;216:43-51
14、Chu X#, Chen W#, Li N, Hu XZ, Du CT, Yu SX, Zhou M, Zhang XJ, Jiang GM, Han WY, Deng XM, Yang YJ. Cytosolic double-stranded DNA induces nonnecroptotic programmed cell death in trophoblasts via IFI16. J Infect Dis. 2014 Nov 1;210(9):1476-86
15、Li SN#, Wang W#, Fu SP#, Wang JF#, Liu HM, Xie SS, Liu BR, Li Y, Lv QK, Li ZQ, Xue WJ, Huang BX, Chen W, Liu JX*. IL-21 modulates release of proinflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Mediators Inflamm.2013;2013:548073
六、科研项目
1、鸡肠道类芽孢杆菌属新种YPG26产新型细菌素抑制产气荚膜梭菌定植的研究(项目批准号:32070119),国家自然科学基金面上项目,58万元,2021.01-2024.12,主持
2、IFI204促进NETs形成以限制金葡菌增殖的研究(项目批准号:31872457),国家自然科学基金面上项目,59万元,2019.01-2022.12,主持
3、沙门菌黏膜感染中核酸识别受体IFI16的调控作用及机制研究(JJKH20170819KJ),吉林省教育厅科学技术研究“十三五”规划课题,3万元,2017.01-2018.12,主持
4、P204信号与金葡菌相互调控的分子机制研究(20160101232JC),吉林省科技厅科技发展计划,10万元,2016.01-2018.12,主要参与人
5、HBV融合蛋白表达与纯化(3R2153446201),横向课题,10万元,2015.01-2017.12,主持
6、沙门氏菌感染过程中AIM2的免疫调控作用及其机制研究 (项目批准号:31372410),国家自然科学基金面上项目,80万元,2014.01-2017.12,主要参与人
七、参译、参编
1、禽类生理学(第6版)/张才乔,杨焕民 主译.-北京:中国农业出版社,2021.12
2、动物生理学实验指导/栾新红 主编.-北京:高等教育出版社,2012.4
3、动物生理学/柳巨雄,杨焕民 主编.-北京:高等教育出版社,2011.7
八、联系方式
邮箱:chw_cc@jlu.edu.cn
发布者:水晶宫,转转请注明出处:https://www.yzydt.com/9340/