邓明田，南京农业大学助理研究员，畜禽繁育专家

　　邓明田，南京农业大学助理研究员，畜禽繁育专家。

一、研究方向

　　动物胚胎发育调控。

二、教育工作简历

　　1、2009/09-2013/06 安徽农业大学动物科学学士
　　2、2013/09-2018/09 南京农业大学动物遗传育种与繁殖农学博士
　　3、2018/12-，南京农业大学动物科技学院师资博士后
　　教授推荐：王子玉，南京农业大学讲师，羊业专家

三、论文

　　1、Mingtian Deng, Baobao Chen, Yingnan Yang, Yongjie Wan, Zifei Liu, Jun Fu, Feng Wang, Characterization of transcriptional activity during ZGA in mammalian SCNT embryo. Biology of reproduction, 2021, ioab127 (IF=4.285)
　　2、Mingtian Deng#, Yongjie Wan#, Zifei Liu, Cai Yu, Baobao Chen, Yanli Zhang, Feng Wang, Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b, Molecular Therapy-Nucleic Acids, 2021,24:54-66（IF=8.886, top10）
　　3、Yu Cai#, Mingtian Deng#, Qifan Zhang, Zifei Liu, Liang Wang, Wenwen Sheng, Yanli Zhang, Peihua You, Ziyu Wang, Feng Wang. Effects of dietary betaine supplementation on biochemical parameters of blood and testicular oxidative stress in Hu sheep. Theriogenology, 2021, 164: 65-73（IF=2.740, top20）
　　4、Mingtian Deng, Baobao Chen, Yongjie Wan, Zifei Liu, Yu Cai, Guoming Zhang, Yixuan Fan, Yanli Zhang and Feng Wang, YTHDF2 Regulates Maternal Transcriptome Degradation and Embryo Development in Goat. Frontiers in Cell and Developmental Biology, 2020, 8: 1040-1050（IF=6.684, top20）
　　5、Mingtian Deng, Baobao Chen, Zifei Liu, Yongjie Wan, Hua Yang, Yu Cai, Jianguo Zhou, Yanli Zhang, Feng Wang. Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos. Theriogenology, 2020, 148: 27-36（IF=2.740，top20）

　　6、Mingtian Deng, Guomin Zhang, Yu Cai, Zifei Liu, Yanli Zhang, Fanxing Meng, Feng Wang, Yongjie Wan, DNA methylation dynamics during zygotic genome activation in goat. Theriogenology, 2020, 156: 144-154（IF=2.740，top20）
　　7、Mingtian Deng, Zifei Liu, BaoBao Chen, Yu Cai, Yongjie Wan, Feng Wang. Locus-Specific Regulation of Xist Expression Using the CRISPR-Cas9-Based System. DNA Cell Biol, 2020, 39(4): 572-578（IF=3.311）
　　8、Mingtian Deng, Baobao Chen, Zifei Liu, Yu Cai, Yongjie Wan, Jianguo Zhou, Feng Wang. Exchanges of histone methylation and variants during mouse zygotic genome activation. Zygote, 2020, 28(1): 51-58
　　9、邓明田, 王锋 (2020). 哺乳动物合子基因组激活调控的研究进展. 黑龙江动物繁殖 28: 37-41.
　　10. Mingtian Deng, Zifei Liu, Caifang Ren, Shiyu An, Yongjie Wan, Feng Wang. Highly methylated Xist in SCNT embryos was retained in deceased cloned female goats. Reproduction, Fertility and Development, 2019, 31(5): 855-866
　　11、Mingtian Deng, Zifei Liu, Caifang Ren, Guomin Zhang, Jing Pang, Yanli Zhang, Feng Wang, Yongjie Wan. Long noncoding RNAs exchange during zygotic genome activation in goat. Biology of reproduction, 2018, 99(4): 707-717（IF= 4.285）
　　12、Mingtian Deng, Caifang Ren, Zifei Liu, Guomin Zhang, Feng Wang, Yongjie Wan. Epigenetic status of H19-Igf2 imprinted genes and loss of 5-hydroxymethylcytosine in the brain of cloned goats. Cellular reprogramming, 2017, 19(3): 199-207
　　13、Yongjie Wan#, Mingtian Deng#, Guomin Zhang, Caifang Ren, Hao Zhang, Yanli Zhang, Lizhong Wang, Feng Wang*. Abnormal expression of DNA methyltransferases and genomic imprinting in cloned goat fibroblasts. Cell biology international, 2016, 40(1): 74-82

四、科研项目

　　1、国家自然科学基金委员会，青年科学基金项目，32102546，LncRNA-loc102177005通过RNA结合蛋白YTHDF2调控山羊合子基因组激活的机制研究，2022/01至2024/12，24万元，在研，主持
　　2、江苏省基础研究计划（自然科学基金）-青年基金，LncRNA lnc-2217对山羊合子基因组激活的表观遗传调控机制研究，2020/07-2023/06，20万，在研，主持
　　3、中国博士后科学基金，Lnc-3712靶向Kdm5b调控山羊核移植胚胎重编程的研究，2019/07-2021/06，8万，在研，主持
　　4、国家自然科学基金面上项目，m6A甲基化修饰参与调控山羊体细胞核移植胚胎母源-合子转换期重编程的研究，2020/1-2023/12，59万，在研，参加
　　5、国家自然科学基金面上项目，LncRNA通过激活TGFβ/SMAD2信号通路调控湖羊垂体促性腺激素分泌的机制研究，2021/1-2024/12，58万，在研，参加