张羽(女),南京农业大学副研究员、硕导。猪繁育专家。
一、研究方向
卵子成熟与胚胎发育。
二、教育工作简历
2004年9月-2009年6月,南京农业大学,动物医学专业 本科
2009年9月-2011年6月,南京农业大学,临床兽医专业 硕士
2011年9月-2014年12月,南京农业大学,临床兽医专业 博士
2015年3月-至今,在南京农业大学动物科技学院任教
教授推荐:汪玥(女),南京农业大学助理研究员,动物繁殖专家
三、科研项目
1、中央高校基本科研业务费,KYYZ202102, PKD1介导的抗氧化参与藏猪卵母细胞高原低氧适应的机制研究,2021/01/01-2021/12/31,5万元,主持
2、国家自然科学基金青年基金项目,31601204,Rab35对小鼠卵母细胞成熟过程中极性形成的调控及机制,2017/01-2019/12,22万元,主持。
3、江苏省自然科学基金青年基金项目,BK20150674,Daam1在猪卵母细胞不均等分裂过程中的功能及机制,2015/07-2018/06,20万元,主持
4、中国博士后科学基金面上资助,2015M580441,Daam1对猪卵母细胞成熟过程中极性形成的调控及机制,2015/12-2017/11,8万元,主持
5、江苏省博士后科研资助计划,1501065B、Rab35对卵母细胞纺锤体迁移和极体排出的功能及机制,2015/08/25-2017/08/24,4万元,主持
6、南京农业大学专任教师科研启动费,802558,2015/10-2017/10,1万元,主持
7、中央高校基本科研业务费,KJQN201703, Rab35对小鼠卵母细胞成熟过程中极性形成的调控及机制,2016/01-2018/12,10万元,主持
8、博士后国际交流计划学术交流项目,2015,3万元,主持
四、奖励荣誉
2019,教育部自然科学二等奖(5/5);
2020,动科院教师教学比赛“二等奖”;
2021,动科院优秀毕业论文指导教师。
五、论文论著
1、Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC. RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis. Mol Hum Reprod. 2019, 25(7):359-372. 2、Zhang Y, Wu LL, Wan X, Wang HH, Li XH, Pan ZN, Sun SC. Loss of PKC mu function induces cytoskeletal defects in mouse oocyte meiosis. J Cell Phyisol. 2019, 234(10):18513-18523.
3、Zhang Y, Wang HH, Wan X, Xu Y, Pan MH, Sun SC. Inhibition of protein kinase D disrupts spindle formation and actin assembly during porcine oocyte maturation. Aging. 2018, 10(12):3736-44. 4、Zhang Y, Wang T, Lan M, Sun SC. Melatonin protects oocytes from MEHP exposure-induced meiosis defects in porcine. Biol Reprod. 2018, 98(3): 286-298.
5、Zhang Y, Wang QC, Liu J, Xiong B, Cui XS, Kim NH, Sun SC. The Small GTPase CDC42 regulates actin dynamics during porcine oocyte maturation. J Reprod Dev. 2017, 63(5): 505-510. 6、Lu YJ#; Zhang Y#, Pan MH, Kim NH, Sun SC, Cui XS. Daam1 regulates fascin for actin assembly in mouse oocyte meiosis. Cell Cycle, 2017, 16(14): 1350-1356. 7、Ma RJ#, Li HR#, Zhang Y#, Lin Y, Qiu XH, Xie M, Yao B. The toxic effects and possible mechanisms of Brusatol on mouse oocytes. PloS One, 2017, 12(5): e0177844.
8、Zhang Y#, Zhu CC#, Sun SC. Cyclin B3: an anaphase onset controller in meiosis. Cell Cycle, 2015, 14(19): 3013.
9、Zhang Y, Wang F, Niu YJ, Liu HL, Rui R, Cui XS, Kim NH, Sun SC. Formin mDia1, a downstream molecule of FMNL1, regulates Profilin1 for actin assembly and spindle organization during mouse oocyte meiosis. BBA Mol Cell Res. 2015, 1853(2): 317-27. 10、Zhang Y, Duan X, Cao R, Liu HL, Cui XS, Kim NH, Rui R, Sun SC. Small GTPase RhoA regulates cytoskeleton dynamics during porcine oocyte maturation and early embryo. Cell Cycle. 2014, 13(21): 3390-403.
11、Zhang Y, Liu J, Peng X, Zhu CC, Han J, Luo J, Rui R. KIF20A Regulates Porcine Oocyte Maturation and Early Embryo Development. PLoS One. 2014, 9(7): e102898. 12、Zhang Y, Wang QC, Han J, Cao R, Cui XS, Kim NH, Rui R, Sun SC. Involvement of Dynamin 2 in actin-based polar body extrusion during porcine oocyte maturation. Mol Reprod Dev. 2014, 81(8):725-34.
13、Zhang Y, Duan X, Xiong B, Cui XS, Kim NH, Rui R, Sun SC. ROCK inhibitor Y-27632 prevents porcine oocyte maturation. Theriogenology. 2014, 82(1):49-56. 14、Pan ZN, Pan MH, Sun MH, Li XH, Zhang Y, Sun SC. RAB7 GTPase regulates actin dynamics for DRP1-mediated mitochondria function and spindle migration in mouse oocyte meiosis. FASEB J. 2020, 34(7): 9615-9627.
15、Pan MH, Wan X, Wang HH, Pan ZN, Zhang Y, Sun SC. FMNL3 regulates FASCIN for actin-mediated spindle migration and cytokinesis in mouse oocytes. Biol Reprod. 2020, 102(6): 1203-1212. 16、Lan M, Zhang Y, Wan X, Pan MH, Xu Y, Sun SC. Melatonin ameliorates ochratoxin A-induced oxidative stress and apoptosis in porcine oocytes. Environ Pollut. 2020. 256:113374.
17、Wang QC, Wan X, Jia RX, Xu Y, Liu X, Zhang Y, Sun SC. Inhibition of N-WASP affects actin-mediated cytokinesis during porcine oocyte maturation. Theriogenology. 2020, 144:132-138. 18、Wang HH, Zhang Y, Tang F, Pan MH, Wan X, Li XH, Sun SC. Rab23/Kif17 regulate meiotic progression in oocytes by modulating tubulin acetylation and actin dynamics. Development. 2019. 146(3): dev171280.
19、Pan ZN, Lu Y, Tang F, Pan MH, Wan X, Lan M, Zhang Y, Sun SC. RAB8A GTPase regulates spindle migration and Golgi apparatus distribution via ROCK-mediated actin assembly in mouse oocyte meiosis. Biol Reprod. 2019, 100(3):711-720. 20、Duan X, Zhang HL, Pan MH, Zhang Y, Sun SC. Vesicular transport protein Arf6 modulates cytoskeleton dynamics for polar body extrusion in mouse oocyte meiosis. BBA-Mol Cell Res. 2018, 1865(2):455-462. (IF=5.3)
六、联系方式
zhangyu77@njau.edu.cn。
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评论列表(1条)
很漂亮的说