程博涵，东北农业大学讲师，家禽遗传育种专家

　　程博涵，东北农业大学讲师。研究方向：家禽遗传育种、表观遗传学。

一、教育工作简历

　　2006.09-2010.06：东北农业大学动物科学专业，学士
　　2010.09-2013.06：东北农业大学动物遗传育种与繁殖专业，硕士
　　2013.09-2017.06：东北农业大学动物遗传育种与繁殖专业，博士
　　2017.09-至今：东北农业大学动物科学技术学院，讲师
　　教授推荐：顾志刚，黑龙江双城市人，东北农业大学讲师，猪遗传育种专家

二、教授课程

　　本科：动物遗传学

三、代表性论文（通讯作者，第一作者，共同第一作者）

　　1、Xinyang Zhang#, Bohan Cheng#, Yanyan Ma, Yumeng Liu, Ning Wang, Hui Zhang Yumao Li, Yuxiang Wang, Peng Luan, Zhiping Cao, Hui Li. Genome-wide survey and functional analysis reveal TCF21 promotes chicken preadipocyte differentiation by directly upregulating HTR2A. Biochem Biophys Res Commun, 2022, 587:131-138. 　　2、Xinyang Zhang#, Bohan Cheng#, Haixu Jiang, Chang Liu, Zhiping Cao, Peng Luan, Ning Wang, Hui Li. Transcription factor 21 promotes chicken adipocyte differentiation at least in part via activating MAPK/JNK signaling. Genes (Basel), 2021, 12 (12):1971.
　　3、Bohan Cheng#, Li Leng#, Ziwei Li, Weijia Wang, Yang Jing, Yudong Li, Ning Wang, Hui Li, Shouzhi Wang. Profiling of RNA N6-Methyladenosine methylation reveals the critical role of m6A in chicken adipose deposition. Front Cell Dev Biol. 2021, 9:590468. 　　4、Chunyan Wu#, Chong Chen, Yumeng Liu, Hui Li, Bohan Cheng. Proteomic analysis of liver tissue between fat and lean broiler lines. Br Poult Sci. 2021, 62(2):211-218
　　5、Lijian Wang#, Li Leng#, Ran Ding, Pengfei Gong, Chang Liu, Ning Wang, Hui Li, Zhi-Qiang Du, Bohan Cheng. Integrated transcriptome and proteome analysis reveals potential mechanisms for differential abdominal fat deposition between divergently selected chicken lines. J Proteomics. 2021, 241:104242.

　　6、Cheng B#, Zhang H#, Liu C, Chen X, Chen Y, Sun Y, Leng L, Li Y, Luan P, Li H. Functional intronic variant in the retinoblastoma 1 gene underlies broiler chicken adiposity by altering nuclear factor-kB and SRY-related HMG box protein 2 binding sites. J Agric Food Chem. 2019, 67(35):9727-9737. 　　7、href=”https://www.ncbi.nlm.nih.gov/pubmed/?term=Chen%20H%5BAuthor%5D&cauthor=true&cauthor_uid=31331641″ Chen H#, Liu C, Liu Y, Li H, Cheng B. Transcription factor HBP1: A regulator of senescence and apoptosis of preadipocytes. Biochem Biophys Res Commun. 2019, 517(2):216-220.
　　8、Chen H#, Liu C, Chen C, Su Z, Shu J, Zhang M, Li H, Cheng B. Bone morphogenetic protein 4 regulates immortalized chicken preadipocyte proliferation by promoting G1/S cell cycle progression. FEBS Open Bio. 2019, 9(6):1109-1118. 　　9、刘畅#, 陈洪艳, 张琦, 张心扬，李辉，程博涵. N6-甲基腺嘌呤RNA修饰研究进展. 中国家禽, 2019, 41(14):50-54.
　　10、Cheng B#, Wu M, Xu S, Zhang X, Wang Y, Wang N, Leng L, Li H. Cocktail supplement with rosiglitazone: a novel inducer for chicken preadipocyte differentiation in vitro. Biosci Rep. 2016, 36(6): e00401. 　　11、Cheng BH#, Leng L#, Wu MQ, Zhang Q, Zhang XY, Xu SS, Cao ZP, Li YM, Luan P, Li H. Expression analysis of bone morphogenetic protein 4 between fat and lean birds in adipose tissue and serum. Domest Anim Endocrinol. 2016, 56: 13-19.

四、在研课题

　　1、鸡BMP4基因在前脂肪细胞增殖中的功能研究（UNPYSCT-2018145）。黑龙江省普通本科高等学校青年创新人才培养计划。课题主持人，2018.08-2021.09
　　2、鸡METTL14基因调控前脂肪细胞分化的机制研究（31902142）。国家自然科学基金青年项目。课题主持人，2020.01-2022.12

五、联系方式

　　邮箱：bhcheng@neau.edu.cn