鲁兴萌，浙江大学动物科学院教授、博导，蚕业、 蚕病专家

　　鲁兴萌，浙江大学动物科学院教授、博导。研究方向：蚕体病理学、 蚕病防治技术。
　　一、教育简历
　　2000.12-浙江大学动物科学学院 教授、副院长等
　　1998.9-浙江大学动物科学学院 副教授、教授
　　1995.5-1998.9 浙江农业大学蚕学系 讲师、副教授、系主任
　　1992.4-1995.3 日本国立京都工艺纤维大学 生物机能科学 博士
　　1991.10-1992.3 日本国立京都工艺纤维大学 微生物与病理学研究室 进修

　　二、工作简历
　　1989.8-1991.10 浙江农业大学蚕学系 病理学研究室 助教、讲师
　　1986.9-1989.7 浙江农业大学蚕学系 家蚕生理与病理学方向 硕士
　　1984.8-1986.8 中国农业科学学院蚕业研究所 生理与病理学研究室 研究员助理
　　1980.9-1984.7 浙江农业大学蚕桑系 学士
　　三、学术兼职
　　中国兽药典第三届委员会委员（2004～）
　　中国蚕学会理事、生理与病理学专业委员会主任（2003～）
　　教育部留学回国人员科研启动基金评审专家（2003～）
　　山东农业大学客座教授（2002～）
　　浙江省农学会理事（2002～）
　　浙江省科协委员（2001～）
　　浙江省蚕桑学会副理事长、学术委员会副主任（1999～）
　　农业部兽药评审委员会委员（1999～）

　　四、主要奖励
　　蚕学专业农工贸复合型人才培养模式的研究和实践，国务院教学改革二等奖， 2001 ， 4/5
　　新型蚕室蚕具消毒剂——消特灵的研究，浙江省科技进步二等奖， 1992 ， 3/5
　　桑蚕细菌性肠道病的研究，浙江农业大学优秀科技成果奖， 1998 ， 1/4
　　浙江省“151人才工程”第二层次（2000～）
　　五、科研项目
　　现主持国家自然科学基金委面上项目（Nosema和Endoreticulatu侵染特异性相关因子的功能与分子特性研究）、农业部公益专项（蚕桑安全生产保障体系的建立，nyhyzx07-02）、教育部博士点基金（家蚕微粒子虫孢子发芽机理相关蛋白因子的研究，20050335009）和其它省部级科研项目5项，地方合作项目1项。参与科技部“973”（家蚕主要经济性状功能基因组与分子改良研究）和“863”（家蚕重要经济性状功能基因的克隆、分子调控与应用研究，2006AA10A119）项目科研工作。在国内外学术刊物发表论。
　　主持农业部岗位科学家，国家自然科学基金委面上项目（Nosema和Endoreticulatu侵染特异性相关因子的功能与分子特性研究）、农业部公益专项（蚕桑安全生产保障体系的建立，nyhyzx07-02）、教育部博士点基金（家蚕微粒子虫孢子发芽机理相关蛋白因子的研究，20050335009）和其它省部级科研项目5项，地方合作项目1项。参与科技部“973”（家蚕主要经济性状功能基因组与分子改良研究）和“863”（家蚕重要经济性状功能基因的克隆、分子调控与应用研究，2006AA10A119）等项目科研工作。

　　六、研究成果
　　蚕学专业农工贸复合型人才培养模式的研究和实践，国务院教学改革二等奖， 2001 ， 4/5
　　新型蚕室蚕具消毒剂——消特灵的研究，浙江省科技进步二等奖， 1992 ， 3/5
　　桑蚕细菌性肠道病的研究，浙江农业大学优秀科技成果奖， 1998 ， 1/4
　　浙江省“151人才工程”第二层次（2000～）
　　七、论文
　　1、Liang, X., et al., Insect symbionts as valuable grist for the biotechnological mill: an alkaliphilic silkworm gut bacterium for efficient lactic acid production. Applied Microbiology and Biotechnology, 2018. 102(11): p. 4951-4962.
　　2、Liang, X., X. Lu, and Y. Shao, Advances in studies on Lepidoptera microsporidium pathogen. Weishengwu Xuebao, 2018. 58(6): p. 1064-1076.
　　3、Chen, B., et al., Comparative shotgun metagenomic data of the silkworm Bombyx mori gut microbiome. Scientific Data, 2018. 5.
　　4、Chen, B., et al., Gut bacterial and fungal communities of the domesticated silkworm (Bombyx mori) and wild mulberry-feeding relatives. Isme Journal, 2018. 12(9): p. 2252-2262.
　　5、Yang, L., X. Lu, and W. Fang, Expression and purification of classical swine fever virus E2 protein from Sf9 cells using a modified vector. Biotechnology Letters, 2017. 39(12): p. 1821-1825.
　　6、Wu, S., et al., Early and simultaneous detection of Nosema bombycis (Microsporidia: Nosematidae), nucleopolyhedrovirus (Baculoviridae), and densovirus (Parvoviridae) by multiplex real-time polymerase chain reaction in Bombyx mori (Lepidoptera: Bombycidae). Canadian Entomologist, 2017. 149(2): p. 265-275.
　　7、Lu, X., et al., Impact of Pebrine-infected Bombyx mori Embryos on Healthy Populations. Acta Sericologica Sinica, 2017. 43(1): p. 68-76.
　　8、Hu, J., et al., SWATH-based quantitative proteomics reveals the mechanism of enhanced Bombyx mori nucleopolyhedrovirus-resistance in silkworm reared on UV-B treated mulberry leaves. Proteomics, 2017. 17(13-14).
　　9、Chen, B.-S., X.-M. Lu, and Y.-Q. Shao, Diversity of the gut microbiota in lepidopteran insects and their interaction with hosts. Acta Entomologica Sinica, 2017. 60(6): p. 710-722.
　　10、Lu, X. and Y. Shao, A Review of Inspection Technology Against Silkworm Pebrine Disease. Acta Sericologica Sinica, 2016. 42(4): p. 717-721.
　　11、Lu, X. and Y. Shao, A Review on Current Status and Development Trend of Pebrine Prevention and Control Technology. Acta Sericologica Sinica, 2016. 42(6): p. 945-952.
　　12、Liu, H., et al., Transcriptome sequencing and characterization of ungerminated and germinated spores of Nosema bombycis. Acta Biochimica Et Biophysica Sinica, 2016. 48(3): p. 246-256.
　　13、Liu, H., et al., Ricin-B-lectin enhances microsporidia Nosema bombycis infection in BmN cells from silkworm Bombyx mori. Acta Biochimica Et Biophysica Sinica, 2016. 48(11): p. 1050-1057.
　　14、Liu, H., et al., Quantitative Proteomic Analysis of Germination of Nosema bombycis Spores under Extremely Alkaline Conditions. Frontiers in Microbiology, 2016. 7.
　　15、Hu, S., et al., Influence of Inspection Lot Scale Type of Silkworm (Bombyx mori) F1 Hybrid Eggs on Pebrine Prevalence. Acta Sericologica Sinica, 2016. 42(2): p. 281-287.
　　16、Fu, Z., et al., Quantitative PCR for detection of Nosema bombycis in single silkworm eggs and newly hatched larvae. Journal of Microbiological Methods, 2016. 120: p. 72-78.
　　17、Chen, B., et al., Biodiversity and Activity of the Gut Microbiota across the Life History of the Insect Herbivore Spodoptera littoralis. Scientific Reports, 2016. 6.
　　18、Chen, B., et al., Draft Genome Sequence of Enterococcus mundtii SL 16, an Indigenous Gut Bacterium of the Polyphagous Pest Spodoptera Littoralis. Frontiers in Microbiology, 2016. 7.
　　19、Zhang, X., et al., DnaJ of Streptococcus suis Type 2 Contributes to Cell Adhesion and Thermotolerance. Journal of Microbiology and Biotechnology, 2015. 25(6): p. 771-781.
　　20、Li, M., et al., Proteomic analysis of silkworm midgut cellular proteins interacting with the 5 ‘ end of infectious flacherie virus genomic RNA. Acta Biochimica Et Biophysica Sinica, 2015. 47(2): p. 80-90.

　　21、He, X., et al., Nosema bombycis (Microsporidia) suppresses apoptosis in BmN cells (Bombyx mori). Acta Biochimica Et Biophysica Sinica, 2015. 47(9): p. 696-702.
　　22、Zhang, X., et al., Changes of mRNA expression of several cytokines in HEp-2 cells infected with Streptococcus suis type 2. Chinase Journal of Preventive Veterinary Medicine, 2014. 36(9): p. 696-700.
　　23、Ye, C., et al., Inhibition of Antiviral Innate Immunity by Birnavirus VP3 Protein via Blockage of Viral Double-Stranded RNA Binding to the Host Cytoplasmic RNA Detector MDA5. Journal of Virology, 2014. 88(19): p. 11154-11165.
　　24、Sun, J., et al., Methyltransferase-Defective Avian Metapneumovirus Vaccines Provide Complete Protection against Challenge with the Homologous Colorado Strain and the Heterologous Minnesota Strain. Journal of Virology, 2014. 88(21): p. 12348-12363.
　　25、He, X., et al., Proteomic analysis of BmN cells (Bombyx mori) in response to infection with Nosema bombycis. Acta Biochimica Et Biophysica Sinica, 2014. 46(11): p. 982-990.
　　26、Lu, X., et al., Epidemiological Survey Methods Based on Testing Environmental Samples of Silkworm Rearing. Acta Sericologica Sinica, 2013. 39(5): p. 913-920.
　　27、Qiu, H., et al., Phylogenetic Analysis of Complete rRNA Gene Sequence of Endoreticulatus sp Shengzhou from the Silkworm, Bombyx mori in Zhejiang of China. Journal of Animal and Veterinary Advances, 2012. 11(7): p. 1056-1062.
　　28、Qiu, H., et al., Identification of Differentially Expressed Genes in BmN Cells Infected by Nosema bombycis and Prokaryotic Expression of Akirin Gene. Acta Sericologica Sinica, 2012. 38(4): p. 673-679.
　　29、Li, M., et al., Detection of an internal translation activity in the 5 ‘ region of Bombyx mori infectious flacherie virus. Applied Microbiology and Biotechnology, 2012. 95(3): p. 697-705.
　　30、Chen, W. and X. Lu, An Investigation on Toxicity and Safety Evaluation of Pesticides to Silkworm,Bombyx mori. Acta Sericologica Sinica, 2012. 38(2): p. 329-336.
　　31、Cai, S.-f., et al., Phagocytic Uptake of Nosema bombycis (Microsporidia) Spores by Insect Cell Lines. Journal of Integrative Agriculture, 2012. 11(8): p. 1321-1326.
　　32、Lu, X., et al., Researches and Applications of PCR Assay Technology in Silkworm Pebrine Disease Diagnosis. Acta Sericologica Sinica, 2011. 37(5): p. 878-882.
　　33、Lu, X., et al., Simulation for the fruit developing period of tomato based on physiological development time. Journal of Northwest A & F University. Natural Science Edition, 2011. 39(12): p. 113-118.
　　34、He, Y.-Q., et al., Influence of DNA extraction methods on detection of Nosema bombycis by traditional PCR and real-time PCR methods. Acta Entomologica Sinica, 2011. 54(11): p. 1329-1334.
　　35、He, Y., et al., Fluorescent Quantitative PCR Detection of Nosema bombycis and the Dignostic Kit. Acta Sericologica Sinica, 2011. 37(2): p. 260-265.
　　36、Cai, S., et al., Identification of a Nosema bombycis (Microsporidia) spore wall protein corresponding to spore phagocytosis. Parasitology, 2011. 138(9): p. 1102-1109.
　　37、Cai, S., et al., A Protocol for Fast and Efficient Preparation of Genomic DNA and Total Proteins of Nosema bombycis. Acta Sericologica Sinica, 2011. 37(6): p. 1019-1024.
　　38、Zhong, R.-j., X.-m. Lu, and Z.-l. Tu, Effects of Environmental Hormone Butyl Benzyl Phthalate on the Development of Silkworm. Asian Journal of Ecotoxicology, 2010. 5(5): p. 673-678.
　　39、Yao, H.-p., et al., Proteomics identification and annotation of proteins of a cell line of Bombyx mori, BmN cells. Bioscience Reports, 2010. 30(3): p. 209-215.
　　40、Wu, X., et al., Phagocytosis of Trichoplusia ni Cultured Cells to Nosema bombycis and the Relationship with Spore Wall Proteins. Acta Sericologica Sinica, 2010. 36(3): p. 447-451.
　　41、Li, M.-q., et al., Genome Analysis of the Bombyx mori Infectious Flacherie Virus Isolated in China. Agricultural Sciences in China, 2010. 9(2): p. 299-305.
　　42、Lang, G.-J., et al., Molecular characterization and inhibition analysis of the acetylcholinesterase gene from the silkworm maggot, Exorista sorbillans. Bmb Reports, 2010. 43(8): p. 573-578.
　　43、Yao, H.-P., et al., Identification of the proteome of the midgut of silkworm, Bombyx mori L., by multidimensional liquid chromatography (MDLC) LTQ-Orbitrap MS. Bioscience Reports, 2009. 29(6): p. 363-373.
　　44、Xie, L., et al., The three-dimensional structure of Infectious flacherie virus capsid determined by cryo-electron microscopy. Science in China Series C-Life Sciences, 2009. 52(12): p. 1186-1191.
　　45、Li, M.-q., et al., Analysis of RNA-Dependent RNA Polymerase Sequence of Infectious Flacherie Virus Isolated in China and Its Expression in BmN Cells. Agricultural Sciences in China, 2009. 8(7): p. 872-879.
　　46、Zhao, N., et al., Efficient production of canine interferon-alpha in silkworm Bombyx mori by use of a BmNPV/Bac-to-Bac expression system. Applied Microbiology and Biotechnology, 2008. 78(2): p. 221-226.
　　47、Yao, H., et al., Gene analysis of an antiviral protein SP-2 from Chinese wild silkworm, Bombyx mandarina Moore and its bioactivity assay. Science in China Series C-Life Sciences, 2008. 51(10): p. 879-884.
　　48、HuiPeng, Y.A.O., et al., Cloning of an Antiviral Protein Gene （Lipase） From Chinese Wild Silkworm, Bombyx mandarina Moore and its Bioactivity Assay. Acta Sericologica Sinica, 2008. 34(3): p. 466-471.
　　49、XingMeng, L.U. and Z. HuaChu, The Relationship Between Nosema bombycis,Other Microsporidia and Fungi. Acta Sericologica Sinica, 2007. 33(2): p. 325-328.
　　50、NaNa, M.A.N., et al., Immunoelectron Micrography of the Midgut Epithelium Infected With Bombyx mori Infectious Flacherie Virus. Acta Sericologica Sinica, 2007. 33(4): p. 602-609.
　　51、Man, N.-N., et al., Cloning and sequence analysis of VP1 gene fragment from a strain of infectious flacherie virus isolated in Zhejiang, China. Acta Entomologica Sinica, 2007. 50(10): p. 1016-1021.
　　52、Lu, Q.-n., et al., Isolation and identification of an infectious flacherie virus from silkworm, Bombyx mori in Zhejiang Province of China. Chinese Journal of Virology, 2007. 23(2): p. 143-147.
　　53、HaiYan, Z., et al., Clone and Phylogenetic Analysis of Partial alpha-Tubulin Gene of Nosema bombycis(Zhejiang Strain). Acta Sericologica Sinica, 2007. 33(1): p. 49-56.
　　54、Wu, X., C. Cao, and X. Lu, Construction of A Rapid BmNPV in Silkworm, Bombyx mori L. Bac-to-Bac System for Application by Using Bacterial Transposon. Acta Sericologica Sinica, 2006. 32(2): p. 183-188,I0001.
　　55、Peihua, J.I.N., H. Lingxia, and L.U. Xingmeng, Emergy analysis of mulberry-silkworm ecosystem in China. CHEN Mingang. The Journal of Applied Ecology, 2006. 17(2): p. 233-236.
　　56、Fei, C., et al., Identification of Enterococcus sp from midgut of silkworm based on biochemical and 16S rDNA sequencing analysis. Annals of Microbiology, 2006. 56(3): p. 201-205.
　　57、Chen, M., et al., Emergy analysis of mulberry-silkworm ecosystem in China. Yingyong Shengtai Xuebao, 2006. 17(2): p. 233-236.
　　58、Chen, F.E.I., et al., Identification of Enterococcus mundtii Isolated From the Intestine of the Silkworm, Bombyx mori. Acta Sericologica Sinica, 2006. 32(3): p. 350-356.
　　59、Cao, C., et al., Development of a rapid and efficient BmNPV baculovirus expression system for application in mulberry silkworm, Bombyx mori. Current Science, 2006. 91(12): p. 1692-1697.
　　60、Zhong, B.X., et al., Analysis of ESTs and gene expression patterns of the posterior silkgland in the fifth instar larvae of silkworm, Bombyx mori L. Science in China Series C-Life Sciences, 2005. 48(1): p. 25-33.
　　61、Wu, X., C. Cao, and X. Lu, Proteolysis of Recombinant Proteins in the Baculovirus Expression Vector System and the Countermeasures. Acta Sericologica Sinica, 2005. 31(4): p. 382-388.
　　62、Wang, Y., et al., RAPD Analysis of the Enterococci Isolated From the Silkworm,Bombyx mori. Acta Sericologica Sinica, 2005. 31(1): p. 59-63.
　　63、Chen, M., et al., Preliminary Evaluation on Sericultural Ecosystem Services and Their Value. Acta Sericologica Sinica, 2005. 31(3): p. 316-320.
　　64、Wu, X.F., et al., Expression of human VEGF165 in silkworm (Bombyx mori L.) by using a recombinant baculovirus and its bioactivity assay. Journal of Biotechnology, 2004. 111(3): p. 253-261.
　　65、Wu, X.F., et al., Construction of a host range-expanded hybrid baculovirus of BmNPV and AcNPV, and knockout of cysteinase gene for more efficient expression. Science in China Series C-Life Sciences, 2004. 47(5): p. 406-415.
　　66、Song, H., X. Lu, and H. Shen, Design of Computer Programm for Diagnosing Silkworm Diseases. Acta Sericologica Sinica, 2004. 30(2): p. 164-170.
　　67、Huang, S., et al., Comparative Study on Spor Surface Proteins of Two Microsporidia and Their Infectivity to Silkworm Bombyx mori. Acta Sericologica Sinica, 2004. 30(2): p. 157-163.
　　68、Huang, S. and X. Lu, Comparative Study on the Infectivity and Spore Surface Protein of Nosema bombycis and Its Morphological Variant Strain. Scientia Agricultura Sinica, 2004. 37(11): p. 1682-1687.
　　69、Wang, F.-W. and X.-M. Lu, Microsporidiosis in insects. Entomological Knowledge, 2003. 40(1): p. 5-8.
　　70、Wang, F., X. Lu, and S. Huang, Kinetic Studies of Enterococci Inhibition on the Germination of Nosema bombycis Spores. Acta Sericologica Sinica, 2003. 29(2): p. 157-161.
　　71、Qing, Y., et al., Observation on the Inoculation and Propagation of the Nosema bombycis in BmN Cell. Acta Sericologica Sinica, 2003. 29(3): p. 260-264.
　　72、Lu, X., et al., Toxicity of Low Dosage Cypermethrin to the Silkworm, Bombyx mori. Chinese journal of pesticide science, 2003. 5(4): p. 42-46.
　　73、Lu, X., et al., Distribution of the Enterococci Isolated From Intestine of the Pebrine Infected Silkworm. Acta Sericologica Sinica, 2003. 29(2): p. 151-156.
　　74、Deng, Y., et al., Ultrastructure of Xiangshan Isolate of White Spot Disease Virus of Penaeus chinensis. Bulletin of Science and Technology, 2003. 19(4): p. 326-329.
　　75、Xu, Y., Z. Xu, and X. Lu, Study Progress of White Spot Syndrome in Penaeus monodon: A Review. Chinese Journal of Veterinary Science and Technology, 2002. 32(1): p. 12-14.
　　76、Singh, G.P., L.X.B. Nataraju, and R.K. Datta, Efficacy of Xiaotelin as a disinfectant against the pathogens of silkworm, Bombyx mori Linn. Indian Journal of Sericulture, 2002. 41(1): p. 84-88.
　　77、Qian, Y., et al., Inhibition of 35 ℃ on the Development and Propagation of the Nosema bombycis in BmN Cells. Science of Sericulture, 2002. 28(1): p. 64-66.
　　78、Lu, X. and F. Wang, Inhibition of Cultured Supernatant of Enterococci Strains on Germination of Nosema bombycis Spores in vitro. Science of Sericulture, 2002. 28(2): p. 126-128.
　　79、Lu, X., et al., Serotyping of Enterococcus faecalis isolated from larval intestine of the silkworm, Bombyx mori. Journal of Sericultural Science of Japan, 1994. 63(4): p. 330-332.
　　80、Lu, X., et al., Taxonomical studies on enterococci isolated from the intestine of the silkworm, Bombyx mori. Journal of Sericultural Science of Japan, 1994. 63(6): p. 481-487.
　　八、出版著作
　　9、鲁兴萌主编. 《蚕桑高新技术研究与进展》（现代农业高新技术成果丛书，国家出版基金项目），ISBN 978-7-5655-0449-5，中国农业大学出版社，753000/469，196~248：家蚕防御功能与养蚕用药物；249~335：家蚕病害诊断与检测技术。224776字。
　　8、《辞海》（普及本）（ISBN 978-7-5326-3105-6/N∙66），上海辞书出版社，2010年8月
　　7、养蚕手册（第2版）。中国农业大学出版社，北京。2005年1月，ISBN 7-81006-828-5/S.608，主编：吴海平、鲁兴萌，35.5万字
　　6、蚕桑标准化生产技术。中国农业大学出版社，2003,ISBN 7-81066-560-X/S.444，鲁兴萌，21.4万字。
　　5、家蚕微粒子病防治的研究。20世纪中国学术大典（农业科学，石元春主编），2002年9月，福建教育出版社（福州），441～442
　　4、简明养蚕手册。2002年4月，中国农业大学出版社（北京），249～290
　　3、家蚕病理学（全国高等农业院校教材，全国高等农业院校教学指导委员会审定）。中国农业出版社，2001年6月出版，主编：金伟；副主编：鲁兴萌：编者：万永继、贡成良、廖富萍。11.6/36.6
　　2、昆虫分子科学，科学出版社，2001年12月，327～365，1.2万字
　　1、蚕桑学实验指导，浙江大学出版社，2001年1月，124～145，3.7万，全书39.7万（缪云根主编）
　　九、联系方式
　　地址：浙江省杭州市西湖区余杭塘路388号浙大紫金港校区农生组团C345
　　邮箱：xmlu@zju.edu.cn